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the prefix that took a stimulant and never came back down

means Excessively active, energetic, or excitedkeyed up past the point of calm.

from From Greek 'hyper,' meaning 'over, above, beyond, exceeding.' It's the natural counterpart to 'hypo' ('under, beneath') and a likely cousin of Latin 'super,' both tracing back to a Proto-Indo-European root for 'over.' For centuries it lived quietly as a scientific and medical prefix (hyperactive, hypertension), but in casual 20th-century speech it broke loose to stand alone as an adjective for anyone bouncing off the walls.

for instance

hyperloop oneprototype vacuum tube transport company testing in nevada, 2016

hyperbole and a halfwebcomic by allie brosh with 2.5+ million followers since 2010

hyperpopgenre pioneered by 100 gecs with viral hits like 'lizard' in 2020s

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