the.com/nephron

a microscopic plumber filtering your entire blood supply sixty times a day, uncomplaining.

means The nephron is the tiny functional unit of the kidney that filters blood, reclaims what the body needs, and sends the rest off as urine — and you have roughly a million of them per kidney.

from Straight from the Greek nephros, meaning kidney — the same root that gives us nephritis (kidney inflammation) and nephrology (the study of kidneys). The diminutive -on ending lends it the feel of a small unit or particle, fitting for the kidney's microscopic working part. The term entered scientific anatomy in the early 20th century as physiologists mapped the kidney's inner machinery.

count
roughly one million per kidney, no replacements issued
daily output
filters 180 liters, returns nearly all of it
length
each tube stretches about 5 centimeters uncoiled
no regrowth
lost nephrons never come back, ever
loop of henle
the hairpin that lets you survive deserts
for instance

proximal convoluted tubule — reabsorbs 99% of filtered glucose, amino acids, and water in the kidney

loop of henle — creates osmotic gradient in medulla allowing humans to concentrate urine up to 1200 mosm/kg

glomerulus — filters 180 liters of blood daily across capillary bed in bowman's capsule

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